Marine omega-3 fatty acid supplementation decreases inflammatory markers in blood


Marine omega-3 fatty acid supplementation decreases inflammatory markers in blood

Marine omega-3 fatty acid supplementation decreases inflammatory markers in blood

 

At a Glance

The results of a recent meta-analysis show that long-term supplementation with omega-3s reduce blood markers of inflammation and may reduce the risk of chronic inflammatory-related diseases.

Read more about this research below

Inflammation is known to play a role in numerous chronic diseases such as diabetes, cardiovascular disease (CVD), obesity-related diseases, rheumatoid arthritis and other autoimmune diseases. Omega-3 fatty acids have often been linked to benefits regarding these conditions, likely due to their anti-inflammatory function.

In a recent meta-analysis published in the online journal PLoS One, scientists reviewed the literature to determine the effect of marine-derived omega-3s on blood levels of several markers of inflammation.

The meta-analysis included 4,601 participants from 68 randomized, controlled trials of healthy subjects, subjects with chronic autoimmune diseases, and subjects with chronic non-autoimmune diseases (ie. cardiovascular disease). Fasting blood levels of the inflammatory markers TNF-a (tumor necrosis factor-alpha), IL-6 (interleukin-6) and CRP (C-reactive protein) were compiled and analyzed. Researchers also separated studies using omega-3s from supplementation as active treatment with those using omega-3s from dietary intake (fish) and included them into different meta-analyses.

A combined analysis of all study subjects revealed a significant link between omega-3 supplementation and decreased blood levels of CRP and IL-6. Among the subjects with chronic non-autoimmune disease, a longer duration of supplementation related to an even greater reduction in blood levels of IL-6 and TNF-a. A similar finding was observed for IL-6 among healthy subjects. Higher dietary intake of omega-3s did result in lower IL-6 levels, but fish intake alone (without supplementation) did not appear to lower CRP or TNF-a. The benefits of omega-3 supplementation were also more significant in non-obese subjects (BMI <30), particularly in the chronic non-autoimmune disease group.

The results of this study confirm that long-term supplementation of omega-3s from fish oil can effectively lower inflammatory markers and may help reduce the risk of chronic inflammation.

Li K, Huang T, Zheng J, Wu K, Li D (2014) Effect of Marine-Derived n-3 Polyunsaturated Fatty Acids on C-Reactive Protein, Interleukin 6 and Tumor Necrosis Factor a: A Meta-Analysis. PLoS ONE 9(2): e88103.


About Chris

My name is Chris Poorten and I believe we have all been put on this earth for a purpose, and we all have many great strengths and talents to share with the world. Our lives are meant to be led with abundance, TRUE HEALTH, and service to others. I am very passionate about helping others there own desired lifestyle Throughout my life I have had an interest in psychology, human behavior, what makes people do different things and why some people become more successful than others. I first picked up the book “Rich Dad Poor Dad” by Robert Kiyosaki around 2001/2002 and it really changed how I viewed jobs, making money, and how one approaches life. One of the main concepts in the book is the importance and benefits of entrepreneurship to create assets that will generate long term income. Over the course of my life I have held many different types of jobs, some of which I enjoyed, and others where I did not feel very happy or fulfilled inside. As a result of this, I decided to use some of the lessons from Rich Dad Poor Dad and look into opportunities to make money outside of a regular job. In doing so, I learned that there is an abundance of opportunities available to earn money and even create true FINANCIAL FREEDOM for yourself. After researching many different options I fell across with an opportunity that I fell in love with. I am able to utilize my passion for helping people with the ability to improve peoples health and financial well being. I truely enjoy being able to make a positive impact in others lives, while helping others do the same. I look forward to hearing how I can help you out.

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